Pholcodine has the following interaction information: Isocarboxazid Pholcodine is predicted to increase the risk of CNS excitation or depression when given with isocarboxazid.

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Drug interactions. Do not take Zyban if you have taken a monoamine oxidase inhibitor such as phenelzine, isocarboxazid , or tranylcypromine in the last 14 days 

Serious side effects have been reported with isocarboxazid including: Hypertensive crisis, a life threatening increase in blood pressure.This sometimes fatal side effect can result from taking MAO inhibitors like isocarboxazid with certain drugs and foods (see "Drug Interactions" and "Food Interactions… Xylometazoline is predicted to increase the risk of a hypertensive crisis when given with isocarboxazid. Manufacturer advises avoid and for 14 days after stopping the MAOI. Severity of interaction: Solriamfetol has the following interaction information: Isocarboxazid. Solriamfetol is predicted to increase the risk of a hypertensive crisis when given with isocarboxazid. Manufacturer advises avoid and for 14 days after stopping the MAOI.

Isocarboxazid interactions

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Do not use amoxapine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl,  such as phenelzine, isocarboxazid , or tranylcypromine in the last 14 days. There are also many medications that may interact with Zyban, including but not  Do not use amoxapine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl,  Drug interaction. Tell your doctor Venlafaxine can interact with: * MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc. Läs mer.

Pholcodine is predicted to increase the risk of CNS excitation or depression when given with isocarboxazid. Manufacturer advises avoid and for 14 days after stopping the MAOI. Severity of interaction: Severe Evidence for interaction: Do not use isocarboxazid if you have used another MAO inhibitor in the past 14 days.

Isocarboxazid may increase the hypoglycemic activities of Glyburide. Glycopyrronium: Isocarboxazid may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium. Glymidine: Isocarboxazid may increase the hypoglycemic activities of Glymidine. Granisetron

Drug interactions can be prevented by avoiding unwanted drug combinations. Interactions Food and lifestyle Potentially life-threatening hypertensive crisis can develop in those taking MAOIs who eat tyramine-rich food (such as mature cheese, salami, pickled herring, Bovril ® , Oxo ® , Marmite ® or any similar meat or yeast extract or fermented soya bean extract, and some beers, lagers or wines) or foods containing dopa (such as broad bean pods).

Isocarboxazid interactions

Learn about drug interactions between methamphetamine oral and isocarboxazid oral and use the RxList drug interaction checker to check drug combinations. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media

Isocarboxazid interactions

Severity of interaction: Interaction between dextromethorphan and monoamine oxidase inhibitor therapy with isocarboxazid N Engl J Med . 1988 Dec 22;319(25):1671.

Isocarboxazid interactions

Isocarboxazid is a hydralazine and monoamine oxidase (MAO) inhibitor with antidepressant activity. Isocarboxazid blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine at central aminergic receptors.
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Isocarboxazid is usually given after other antidepressants have been tried without successful treatment of symptoms. Isocarboxazid is a non-selective hydrazine monoamine oxidase (MAO) inhibitor.

This eMedTV page discusses some of the other drugs that may interact with isocarboxazid, including some that may cause dangerous side effects. Pholcodine has the following interaction information: Isocarboxazid Pholcodine is predicted to increase the risk of CNS excitation or depression when given with isocarboxazid. Pseudoephedrine is predicted to increase the risk of a hypertensive crisis when given with isocarboxazid.
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Drug Interactions With Isocarboxazid: An Introduction Isocarboxazid (Marplan ®) can potentially interact with many medicines.Because there are so many isocarboxazid drug interactions that can be very dangerous, it is important to check with your healthcare provider before taking any medication, whether prescription or over-the-counter.

Isocarboxazid may impair your thinking or Do not use isocarboxazid if you have used another MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others. Some young people have thoughts about suicide when first taking an antidepressant.


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The cause of the interactions is because MAOIs inhibit the metabolism of dietary amines (e.g., tyramine) and the monoamine neurotransmitters. In combination with 

Manufacturer advises avoid and for 14 days after stopping the MAOI. Severity of interaction: Solriamfetol has the following interaction information: Isocarboxazid. Solriamfetol is predicted to increase the risk of a hypertensive crisis when given with isocarboxazid.

Isocarboxazid is predicted to increase the risk of antimuscarinic adverse effects when given with acrivastine. Manufacturer advises avoid. Severity of interaction:  

Periactin interact with such medication as: isocarboxazid (Marplan); phenelzine (Nardil); rasagiline (Azilect); selegiline (Eldepryl, Emsam); or  Drug interaction. Tell your doctor Escitalopram can interact with: * MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc. Drug interaction. Periactin interact with such medication as: isocarboxazid (Marplan); phenelzine (Nardil); rasagiline (Azilect); selegiline (Eldepryl, Emsam); or  Periactin interact with such medication as: isocarboxazid (Marplan); with your doctor about how it interactions are being managed or should be managed. Bupropion can interact with: * MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc. * antiarrhythmics * antipsychotics Interaction of Sumatriptan and MAO inhibitors (isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane)) is also  use before using this medication.

Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco. Isocarboxazid, like the other MAOIs, can cause a variety of side effects apart from the food interactions described above. Common side effects include dizziness and fainting associated with low blood pressure when standing up (orthostatic hypotension), sexual dysfunction, anxiety , headache, nausea, sleep disturbances, edema, constipation, and weight gain. isocarboxazid oral and phenelzine oral both increase affecting serotonin levels in the blood. Too much serotonin is a potentially life-threatening situation. Severe signs and symptoms include high blood pressure and increased heart rate that lead to shock.